The effects of tetrahydrocurcumin compared to curcuminoids on human platelet aggregation and blood coagulation in vitro

Kent Chapman; Fiona E Scorgie; Anita Ariyarajah; Eleanor Stephens; Anoop K Enjeti; Lisa F Lincz

doi:10.1016/j.thromres.2019.04.029

The effects of tetrahydrocurcumin compared to curcuminoids on human platelet aggregation and blood coagulation in vitro

Thromb Res. 2019 Jul:179:28-30. doi: 10.1016/j.thromres.2019.04.029. Epub 2019 Apr 30.

Authors

Kent Chapman¹, Fiona E Scorgie², Anita Ariyarajah², Eleanor Stephens³, Anoop K Enjeti⁴, Lisa F Lincz⁵

Affiliations

¹ NSW Health, Pathology North-Hunter, NSW, Australia.
² Haematology Department, Calvary Mater Newcastle, Australia; Hunter Medical Research Institute, New Lambton, Australia; Hunter Cancer Research Alliance, NSW, Australia.
³ Haematology Department, Calvary Mater Newcastle, Australia.
⁴ NSW Health, Pathology North-Hunter, NSW, Australia; Haematology Department, Calvary Mater Newcastle, Australia; School of Medicine and Public Health, University of Newcastle, Australia; Hunter Medical Research Institute, New Lambton, Australia; Hunter Cancer Research Alliance, NSW, Australia.
⁵ Haematology Department, Calvary Mater Newcastle, Australia; Hunter Medical Research Institute, New Lambton, Australia; Hunter Cancer Research Alliance, NSW, Australia; School of Biomedical Sciences and Pharmacy, University of Newcastle, Australia. Electronic address: [email protected].

PMID: 31075698
DOI: 10.1016/j.thromres.2019.04.029

No abstract available

Keywords: APTT; Bisdemethoxycurcumin (BDMC); Curcumin; Demethoxycurcumin (DMC); Diferuloylmethane; PT; Platelet aggregation; Tetrahydrocurcumin (THC).

Publication types

Letter

MeSH terms

Blood Coagulation / drug effects*
Curcumin / analogs & derivatives*
Curcumin / pharmacology
Curcumin / therapeutic use
Diarylheptanoids / pharmacology
Diarylheptanoids / therapeutic use*
Humans
Platelet Aggregation / drug effects*
Platelet Function Tests / methods*

Substances

Diarylheptanoids
tetrahydrocurcumin
Curcumin