Autoimmune necrotizing myopathy after statin discontinuation

BMJ Case Rep. 2019 May 15;12(5):e229656. doi: 10.1136/bcr-2019-229656.

Abstract

We report a case of autoimmune necrotizing myopathy related to statin use in a 70-year-old woman who came to the hospital because of progressive lower extremity weakness. Laboratory, electromyography and muscle biopsy results were consistent with autoimmune necrotising myopathy. The patient was treated with intravenous immunoglobulin with improvement in muscle strength.

Keywords: muscle disease; unwanted effects/adverse reactions.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Autoimmune Diseases / chemically induced*
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
  • Muscular Diseases / chemically induced*
  • Necrosis / chemically induced*
  • Substance Withdrawal Syndrome / diagnosis

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors