Three-dimensional MRI sequences in MS diagnosis and research

Xun Yang Hu; Luckshi Rajendran; Emmanuelle Lapointe; Roger Tam; David Li; Anthony Traboulsee; Alexander Rauscher

doi:10.1177/1352458519848100

Three-dimensional MRI sequences in MS diagnosis and research

Mult Scler. 2019 Nov;25(13):1700-1709. doi: 10.1177/1352458519848100. Epub 2019 May 22.

Authors

Xun Yang Hu¹, Luckshi Rajendran¹, Emmanuelle Lapointe², Roger Tam³, David Li⁴, Anthony Traboulsee⁵, Alexander Rauscher⁶

Affiliations

¹ Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
² Department of Medicine, Division of Neurology, University of Sherbrooke, Sherbrooke, QC, Canada.
³ Department of Radiology, School of Biomedical Engineering, The University of British Columbia, Vancouver, BC, Canada.
⁴ Department of Radiology, UBC Hospital, Vancouver, BC, Canada.
⁵ Division of Neurology, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
⁶ Department of Radiology, The University of British Columbia, Vancouver, BC, Canada.

PMID: 31116071
DOI: 10.1177/1352458519848100

Abstract

The most recent guidelines for magnetic resonance imaging (MRI) in multiple sclerosis (MS) recommend three-dimensional (3D) MRI sequences over their two-dimensional (2D) counterparts. This development has been made possible by advances in MRI scanner hardware and software. In this article, we review the 3D versions of conventional sequences, including T1-weighted, T2-weighted and fluid-attenuated inversion recovery (FLAIR), as well as more advanced scans, including double inversion recovery (DIR), FLAIR², FLAIR*, phase-sensitive inversion recovery, and susceptibility weighted imaging (SWI).

Keywords: MRI; multiple sclerosis.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Humans
Imaging, Three-Dimensional / methods*
Magnetic Resonance Imaging / methods*
Multiple Sclerosis / diagnostic imaging*
Neuroimaging / methods*