Background: We sought to investigate the clinical features and 18 F-FDG PET/CT characteristics of pulmonary sclerosing pneumocytoma (PSP).
Methods: We retrospectively reviewed and comparatively analyzed 18 F-FDG PET/CT imaging results of 22 patients with diagnosed PSP in our hospital from November 2009 to September 2015.
Results: The SUVmax in tumors was positively correlated with tumor size in typical PSPs (R = 0.806, R2 = 0.650, P = 0.001); however, the SUVmax in tumors had no significant correlation with tumor size of atypical PSPs (R = 0.479, R2 = 0.229, P = 0.162), and the degree of correlation between them attenuated when atypical PSPs were included (R = 0.518, R2 = 0.268, P = 0.011). A majority (90%) of atypical PSPs were found in males. Symptomatic patients showed a higher SUVmax than the asymptomatic group (5.68 ± 3.63 vs. 2.76 ± 1.18, respectively, P = 0.002).
Conclusion: Tumor size and clinical features may be associated with increased FDG uptake in PSPs. Morphological differences may affect the correlation between tumor size and SUVmax in PSPs. The atypical form of PSP may be more common in men.
Keywords: 18Fluorine 2-fluoro-2-deoxy-d-glucose; positron emission tomography and computed tomography; pulmonary sclerosing pneumocytoma.
© 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.