Unexpected analytical interference in isavuconazole UV determination in a child in therapy with lumacaftor/ivacaftor for cystic fibrosis

Clin Chem Lab Med. 2019 Oct 25;57(11):e274-e278. doi: 10.1515/cclm-2019-0192.
No abstract available

Keywords: high performance liquid chomatography; isavuconazole; lumacaftor; therapeutic drug monitoring.

Publication types

  • Letter

MeSH terms

  • Aminophenols / pharmacology
  • Aminophenols / therapeutic use*
  • Aminopyridines / pharmacology
  • Aminopyridines / therapeutic use*
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / pharmacology
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Benzodioxoles / pharmacology
  • Benzodioxoles / therapeutic use*
  • Cystic Fibrosis / drug therapy*
  • Cystic Fibrosis / pathology
  • Female
  • Humans
  • Male
  • Nitriles / pharmacology
  • Nitriles / therapeutic use*
  • Pyridines / pharmacology
  • Pyridines / therapeutic use*
  • Quinolones / pharmacology
  • Quinolones / therapeutic use*
  • Triazoles / pharmacology
  • Triazoles / therapeutic use*

Substances

  • Aminophenols
  • Aminopyridines
  • Antifungal Agents
  • Benzodioxoles
  • Nitriles
  • Pyridines
  • Quinolones
  • Triazoles
  • ivacaftor
  • isavuconazole
  • lumacaftor