Influence of a resin-based blood culture medium on the time to clearance of methicillin-susceptible Staphylococcus aureus bloodstream infection - A retrospective cohort study

Nicolas Gürtler; Anthea Denz; Adrian Egli; Andreas F Widmer; Michael Osthoff

doi:10.1016/j.diagmicrobio.2019.04.010

Influence of a resin-based blood culture medium on the time to clearance of methicillin-susceptible Staphylococcus aureus bloodstream infection - A retrospective cohort study

Diagn Microbiol Infect Dis. 2019 Sep;95(1):25-27. doi: 10.1016/j.diagmicrobio.2019.04.010. Epub 2019 May 2.

Authors

Nicolas Gürtler¹, Anthea Denz², Adrian Egli³, Andreas F Widmer⁴, Michael Osthoff⁵

Affiliations

¹ Division of Internal Medicine, University Hospital Basel, Basel, Switzerland. Electronic address: [email protected].
² Division of Internal Medicine, University Hospital Basel, Basel, Switzerland.
³ Division of Clinical Microbiology, University Hospital Basel, Basel, Switzerland; Department of Biomedicine, University Basel, Basel, Switzerland.
⁴ Department of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
⁵ Division of Internal Medicine, University Hospital Basel, Basel, Switzerland; Department of Biomedicine, University Basel, Basel, Switzerland.

PMID: 31155394
DOI: 10.1016/j.diagmicrobio.2019.04.010

Abstract

We evaluated the improved sensitivity and time to detection of new resin-based blood culture (BC) media in Staphylococcus aureus bloodstream infection. We observed a significantly longer duration of bacteremia and shorter time to detection compared to traditional charcoal-based BC media, which may influence diagnostic work-up and treatment duration.

Keywords: Bacteremia; Resin-based blood culture media; Staphylococcus aureus; Time to clearance.

Publication types

Comparative Study

MeSH terms

Aged
Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use
Bacteremia / drug therapy*
Bacteremia / microbiology
Blood Culture*
Culture Media / chemistry*
Female
Humans
Male
Methicillin / pharmacology*
Methicillin / therapeutic use*
Middle Aged
Retrospective Studies
Staphylococcal Infections / drug therapy*
Staphylococcal Infections / microbiology
Staphylococcus aureus / drug effects*
Staphylococcus aureus / isolation & purification
Time Factors

Substances

Anti-Bacterial Agents
Culture Media
Methicillin