Differentiating Right- and Left-Sided Outflow Tract Ventricular Arrhythmias: Classical ECG Signatures and Prediction Algorithms

Circ Arrhythm Electrophysiol. 2019 Jun;12(6):e007392. doi: 10.1161/CIRCEP.119.007392. Epub 2019 Jun 4.

Abstract

Idiopathic ventricular arrhythmias commonly originate from the right ventricular and left ventricular outflow tracts (OTs). Advances in real-time imaging have refined our understanding of the intimate anatomic structures implicated in the genesis of OT arrhythmias, making catheter ablation for arrhythmias beyond the right ventricular OT a feasible option for cure-indeed ablation is now a class I indication in recent guidelines. The surface 12-lead ECG is routinely used to localize the anatomic site of origin before catheter ablation. However, the intimate and complex anatomy of the OT limits predictive value ECG criteria alone for localization for these arrhythmias. Multiple ECG algorithms have been developed to assist preprocedural localization, and hence predict safety and efficacy for catheter ablation of OT ventricular arrhythmias. This review will summarize all of the published 12-lead ECG algorithms used to guide localization of OT ventricular arrhythmias.

Keywords: algorithms; cardiac arrhythmia; catheter ablation; electrocardiography.

Publication types

  • Review

MeSH terms

  • Action Potentials
  • Adolescent
  • Adult
  • Aged
  • Algorithms
  • Arrhythmias, Cardiac / diagnosis*
  • Arrhythmias, Cardiac / physiopathology
  • Diagnosis, Differential
  • Electrocardiography*
  • Female
  • Heart Rate*
  • Heart Ventricles / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prognosis
  • Signal Processing, Computer-Assisted
  • Ventricular Function, Left*
  • Ventricular Function, Right*
  • Young Adult