Developing a Diagnostic Algorithm for the Music-Based Scale for Autism Diagnostics (MUSAD) Assessing Adults with Intellectual Disability

J Autism Dev Disord. 2019 Sep;49(9):3732-3752. doi: 10.1007/s10803-019-04069-y.

Abstract

Initial studies have presented the Music-based Scale for Autism Diagnostics (MUSAD) as a promising DSM-5-based observational tool to identify autism spectrum disorder (ASD) in adults with intellectual disability (ID). The current study is the first to address its clinical utility in a new sample of 124 adults with ID (60.5% diagnosed with ASD). The derived diagnostic algorithm differentiated well between individuals with and without ASD (sensitivity 79%, specificity 74%, area under the curve = 0.81). Inter-rater reliability, assessed by the scorings of four independent experts in 22 consensus cases, was excellent (ICC = 0.92). Substantial correlations with scores from other ASD-specific measures indicated convergent validity. The MUSAD yields accurate and reliable scores, supporting comprehensive ASD diagnostics in adults with ID.

Keywords: Adults; Autism spectrum disorder; Diagnostic; Intellectual disability; Music.

Publication types

  • Validation Study

MeSH terms

  • Adult
  • Algorithms*
  • Area Under Curve
  • Autism Spectrum Disorder / diagnosis*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Humans
  • Intellectual Disability / diagnosis*
  • Male
  • Music / psychology*
  • Psychological Tests / statistics & numerical data*
  • Reproducibility of Results
  • Sensitivity and Specificity