T2*-Weighted MRI Detected Dilated Cerebral Veins in a Patient with Acute-Phase Cerebral Venous Sinus Thrombosis-A Case Report

J Stroke Cerebrovasc Dis. 2019 Aug;28(8):e116-e118. doi: 10.1016/j.jstrokecerebrovasdis.2019.05.024. Epub 2019 Jun 3.

Abstract

We describe a 45-year-old man who presented with nausea, vomiting, and strong occipital headache on the right side. Although no abnormalities on neurological examination or computed tomography imaging were found on admission, peripheral blood cell counts showed polycythemia (hemoglobin 20.6 g/dL) and electrocardiography demonstrated atrial fibrillation. Therefore, anticoagulant treatment with heparin was started immediately. On the following day, the occipital headache continued. Brain T2*-weighted (T2*WI) magnetic resonance imaging (MRI) and, to a lesser extent, susceptibility-weighted imaging showed dilation of numerous cortical veins, suggesting the possibility of cerebral venous thrombosis (CVT). MR venography (MRV) showed a deficit of the right transverse sinus. Contrast-enhanced MRI revealed partial defects of the right transverse sinus, and led to the definite diagnosis of CVT, and the anticoagulation therapy was continued. On day 7 the headache disappeared, and MRV on day 16 showed the recanalization of the right transverse sinus. There were no complications subsequent to the CVT. On day 25, the patient was discharged with no after-effect. We speculate that the dilation of cortical veins on T2*WI is a helpful sign in detecting acute-phase CVT.

Keywords: Acute cerebral venous thrombosis; T2*-weighted MRI; anticoagulant; diagnosis; dilation.

Publication types

  • Case Reports

MeSH terms

  • Anticoagulants / therapeutic use
  • Cerebral Angiography / methods
  • Cerebral Veins / diagnostic imaging*
  • Cerebral Veins / pathology
  • Diffusion Magnetic Resonance Imaging*
  • Dilatation, Pathologic
  • Heparin / therapeutic use
  • Humans
  • Magnetic Resonance Angiography
  • Male
  • Middle Aged
  • Phlebography / methods
  • Predictive Value of Tests
  • Sinus Thrombosis, Intracranial / diagnostic imaging*
  • Sinus Thrombosis, Intracranial / drug therapy
  • Sinus Thrombosis, Intracranial / pathology
  • Treatment Outcome

Substances

  • Anticoagulants
  • Heparin