Phytosynthesis of silver nanoparticles using Mangifera indica flower extract as bioreductant and their broad-spectrum antibacterial activity

Bioorg Chem. 2019 Jul:88:102970. doi: 10.1016/j.bioorg.2019.102970. Epub 2019 May 2.

Abstract

The present study focused on the evaluation of antibacterial property of silver nanoparticles (AgNPs) synthesized using mango flower extract. The morphology of the synthesized AgNPs was observed under transmission electron microscopy and the particles have shown spherical shape in the range of 10-20 nm. X-ray powder diffraction analysis confirmed the crystalline nature of the AgNPs. The atomic percentage of the Ag element in the nanoparticles was about 7.58% which is greater than the other elements present in the sample. The AgNPs showed extensive lethal effect on both Gram-positive (Staphylococcus sp.) and Gram-negative (Klebsiella sp., Pantoea agglomerans, and Rahnella sp.) bacteria. The extensive lethal effect of AgNPs against clinically important pathogens demonstrated that the mango flower mediated AgNPs could be applied as potential antibacterial agent to control the bacterial population in the respective industries.

Keywords: Antibacterial; Bacterial infections; Broad-spectrum; Mango flower; Silver nanoparticles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / metabolism
  • Anti-Bacterial Agents / pharmacology*
  • Dose-Response Relationship, Drug
  • Flowers / chemistry
  • Flowers / metabolism*
  • Klebsiella / drug effects
  • Mangifera / chemistry
  • Mangifera / metabolism*
  • Metal Nanoparticles / chemistry*
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Pantoea / drug effects
  • Particle Size
  • Plant Extracts / chemistry
  • Plant Extracts / metabolism
  • Plant Extracts / pharmacology*
  • Rahnella / drug effects
  • Silver / chemistry
  • Silver / metabolism
  • Silver / pharmacology*
  • Staphylococcus / drug effects
  • Structure-Activity Relationship
  • Surface Properties

Substances

  • Anti-Bacterial Agents
  • Plant Extracts
  • Silver