Abstract
A large and diverse group of coagulase-negative staphylococci were assayed for the ability to produce toxic shock syndrome toxin 1 (TSST-1) by immunological reactivity, and whole-cell DNAs from 33 of these strains were hybridized with a TSST-1-specific gene probe. None of the strains tested, including isolates that have been reported as TSST-1+, produced the exotoxin, and no DNA homology was found with the gene probe.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Toxins*
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Coagulase / metabolism
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DNA, Bacterial / analysis*
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Enterotoxins / biosynthesis*
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Enterotoxins / genetics
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Immunodiffusion
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Nucleic Acid Hybridization
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Sequence Homology, Nucleic Acid
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Staphylococcus aureus / enzymology
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Staphylococcus aureus / genetics
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Staphylococcus aureus / metabolism*
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Superantigens*
Substances
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Bacterial Toxins
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Coagulase
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DNA, Bacterial
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Enterotoxins
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Superantigens
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enterotoxin F, Staphylococcal