[Drug-induced hepatitis caused by Fansidar]

Schweiz Med Wochenschr. 1987 Oct 3;117(40):1544-8.
[Article in German]

Abstract

We report on a 27-year-old patient with recurrent cholestatic hepatitis in whom the symptoms developed each time after travelling in tropical areas. Our primary diagnosis was recurrent non-A-non-B-hepatitis after exclusion of other forms of infectious hepatitis, but careful exploration identified Fansidar as the causative agent of liver damage.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antimalarials / adverse effects*
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / pathology
  • Diagnosis, Differential
  • Drug Combinations / adverse effects
  • Hepatitis C / diagnosis
  • Humans
  • Liver / pathology
  • Liver Function Tests
  • Male
  • Pyrimethamine / adverse effects*
  • Sulfadoxine / adverse effects*
  • Sulfanilamides / adverse effects*

Substances

  • Antimalarials
  • Drug Combinations
  • Sulfanilamides
  • fanasil, pyrimethamine drug combination
  • Sulfadoxine
  • Pyrimethamine