Addison's disease: immunological aspects

Tissue Antigens. 1987 Jul;30(1):23-4.

Abstract

The frequency of HLA DR3 in patients with Addison's disease is increased and the relative risk factor rises to 10 when adrenocortical failure is part of a polyendocrinopathy.

MeSH terms

  • Addison Disease / immunology*
  • Adrenal Cortex / immunology
  • Autoimmune Diseases / immunology*
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 2 / complications
  • Endocrine Glands / immunology
  • Endocrine System Diseases / complications
  • Gene Frequency
  • Genes, MHC Class I
  • Genes, MHC Class II
  • HLA Antigens / analysis
  • HLA-B8 Antigen
  • HLA-DR Antigens / analysis
  • Humans
  • Islets of Langerhans / immunology
  • Thyroid Diseases / complications

Substances

  • HLA Antigens
  • HLA-B8 Antigen
  • HLA-DR Antigens