Abstract
Recombination at the immunoglobulin kappa light chain locus creates a complete variable region gene and its reciprocal product. The results presented here show that reciprocal products may be substrates for secondary recombination and that at least one V kappa group rearranges by inversion.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Antibody Diversity
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Base Sequence
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Genes, Immunoglobulin*
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Immunoglobulin J-Chains / genetics
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Immunoglobulin Switch Region / genetics
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Immunoglobulin Variable Region / genetics
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Immunoglobulin kappa-Chains / genetics
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Mice
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Models, Genetic*
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Molecular Sequence Data
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Plasmacytoma / pathology
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Recombination, Genetic*
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Tumor Cells, Cultured
Substances
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Immunoglobulin J-Chains
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Immunoglobulin Variable Region
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Immunoglobulin kappa-Chains
Associated data
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GENBANK/M18406
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GENBANK/M18407
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GENBANK/M18408
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GENBANK/M18409