Serum biomarkers for sepsis in children with febrile neutropenia and cancer

A Ruggiero; K Pocino; M Catalano; P Maurizi; M D'Ambra; D Rizzo; S Triarico; G Attinà; S Mastrangelo; E D Capoluongo

Serum biomarkers for sepsis in children with febrile neutropenia and cancer

J Biol Regul Homeost Agents. 2019 May-Jun;33(3):999-1003.

Authors

A Ruggiero^#¹, K Pocino^#², M Catalano¹, P Maurizi¹, M D'Ambra¹, D Rizzo¹, S Triarico¹, G Attinà¹, S Mastrangelo¹, E D Capoluongo²

Affiliations

¹ Pediatric Oncology Unit, Fondazione Policlinico A. Gemelli IRCCS - Università Cattolica Sacro Cuore, Rome, Italy.
² Institute of Clinical Biochemistry, Fondazione Policlinico A. Gemelli IRCCS - Università Cattolica Sacro Cuore, Rome, Italy.

^# Contributed equally.

PMID: 31198017

Abstract

The National Institute for Health and Care Excellence (NICE) defines febrile neutropenia or "neutropenic sepsis" as a patient with an absolute neutrophil count (ANC) less than 0.5 x 109/L and temperature >38°C or signs and symptoms of sepsis.

Keywords: children; febrile neutropenia; presepsin; procalcitonin; sepsis.

Publication types

Letter

MeSH terms

Biomarkers / blood*
Child
Febrile Neutropenia / blood*
Humans
Leukocyte Count
Neoplasms / blood*
Sepsis / blood
Sepsis / diagnosis*

Substances

Biomarkers