Rearranged clerodane diterpenoid from Tinospora crispa

Nat Prod Res. 2021 Feb;35(3):369-376. doi: 10.1080/14786419.2019.1633648. Epub 2019 Jun 27.

Abstract

A new rearranged clerodane diterpenoid, tinocrispide was isolated from the stems of Tinospora crispa along with thirteen known compounds including eight clerodane diterpenoids. Among the known compounds baenzigeride A, (6S, 9 R)-vomifoliol and steponine are being reported for the first time from T. crispa. Their structures were elucidated by 1 D and 2 D NMR and confirmed by HRESIMS. The 13C NMR data of borapetol A has been revised.

Keywords: NMR; Tinospora crispa; borapetol A; isolation; tinocrispide.

MeSH terms

  • Diterpenes, Clerodane / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Extracts / chemistry
  • Spectrometry, Mass, Electrospray Ionization
  • Tinospora / chemistry*

Substances

  • Diterpenes, Clerodane
  • Plant Extracts