Comparable clinical outcome and implant longevity after CT- or MRI-based patient-specific instruments for total knee arthroplasty: a 2-year follow-up of a RCT

Knee Surg Sports Traumatol Arthrosc. 2020 Jun;28(6):1821-1826. doi: 10.1007/s00167-019-05616-x. Epub 2019 Jul 3.

Abstract

Purpose: Patient-specific instruments (PSI) are already widespread used in total knee arthroplasty (TKA). Either computed tomography (CT) scans or magnetic resonance imaging (MRI) scans are used pre-operatively to create jigs to guide resection during surgery. This study is a sequel of previous work that showed significantly more radiological outliers for posterior slope when CT-based guides were used. The aim of this study was to assess differences in revision rate and clinical outcome between the two groups at 2-year follow-up.

Methods: At the 2-year follow-up, 124 patients were analysed in this prospective, randomised single-blind study. A survival analysis with revision of the TKA as endpoint was performed. Patients fulfilled four patient-reported outcome measurements (PROMs). Scores on the questionnaires were compared between both groups at the different follow-up visits.

Results: At final follow-up, there was no significant difference in the survival rates of the CT- and MRI-based PSI surgery. Postoperatively, the PROMs significantly improved within each group compared with the pre-operative values. There were no significant differences for the PROMs between both groups at the 2-years follow-up.

Conclusions: Although previous results showed more outliers regarding posterior slope for CT-based PSIs, no difference in revision rate or the outcome of PROMs was found at 2-year follow-up. Further research to determine what the influence is of radiological outliers on implant survival and clinical outcomes is necessary.

Level of evidence: I.

Keywords: CT; Clinical outcome; Computed tomography; MRI; Magnetic resonance imaging; PSI; Patients-specific instruments; Revision rate; Survival; Total knee arthroplasty; Total knee replacement.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Arthroplasty, Replacement, Knee / instrumentation*
  • Arthroplasty, Replacement, Knee / methods*
  • Equipment Failure Analysis*
  • Female
  • Follow-Up Studies
  • Humans
  • Knee Joint / surgery
  • Knee Prosthesis*
  • Magnetic Resonance Imaging*
  • Male
  • Osteoarthritis, Knee / surgery
  • Patient Reported Outcome Measures
  • Prospective Studies
  • Reoperation
  • Single-Blind Method
  • Surgery, Computer-Assisted / methods*
  • Tomography, X-Ray Computed*