Inhibition of ATP binding cassette transporter B1 sensitizes human hair follicles to chemotherapy-induced damage

J Dermatol Sci. 2019 Jul;95(1):44-47. doi: 10.1016/j.jdermsci.2019.06.003. Epub 2019 Jun 14.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B / antagonists & inhibitors
  • ATP Binding Cassette Transporter, Subfamily B / metabolism
  • Alopecia / chemically induced
  • Alopecia / pathology
  • Alopecia / prevention & control
  • Antineoplastic Agents / toxicity*
  • Apoptosis / drug effects
  • Cell Culture Techniques
  • Cyclophosphamide / analogs & derivatives
  • Cyclophosphamide / toxicity
  • Doxorubicin / toxicity
  • Hair Follicle / drug effects*
  • Hair Follicle / metabolism
  • Humans
  • Scalp
  • Verapamil / pharmacology

Substances

  • ABCB1 protein, human
  • ATP Binding Cassette Transporter, Subfamily B
  • Antineoplastic Agents
  • 4-hydroxycyclophosphamide
  • Doxorubicin
  • Cyclophosphamide
  • Verapamil