Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS

Molecules. 2019 Jul 10;24(14):2519. doi: 10.3390/molecules24142519.

Abstract

Zornia brasiliensis Vogel (Leguminosae) is a species popularly known in Brazil as "urinária", "urinana", and "carrapicho", it is popularly used as a diuretic and in the treatment of venereal diseases. A specific methodology to obtain a saponin-enriched fraction and high-performance liquid chromatography coupled with diode array detection, ion trap mass spectrometry, and TOF-MS (HPLC-DAD-ESI-MS/MS) was applied for the analysis of triterpene saponins. The MS and MS/MS experiments were carried out by ionization in negative mode. Molecular mass and fragmentation data were used to support the structural characterization of the saponins. Based on retention times, high-resolution mass determination and fragmentation, 35 oleanane-triterpene saponins were tentatively identified in Z. brasiliensis.

Keywords: HPLC-DAD-ESI-MS/MS; Zornia brasiliensis; soyasaponins; triterpene saponins.

MeSH terms

  • Chromatography, High Pressure Liquid*
  • Fabaceae / chemistry*
  • Magnetic Resonance Spectroscopy
  • Metabolic Networks and Pathways
  • Molecular Structure
  • Plant Extracts / analysis*
  • Plant Extracts / chemistry
  • Saponins / analysis*
  • Saponins / chemistry
  • Spectrometry, Mass, Electrospray Ionization*
  • Tandem Mass Spectrometry*
  • Triterpenes / analysis*
  • Triterpenes / chemistry

Substances

  • Plant Extracts
  • Saponins
  • Triterpenes