First detection and genetic characterization of peste des petits ruminants virus from dorcas gazelles "Gazella dorcas" in the Sudan, 2016-2017

Arch Virol. 2019 Oct;164(10):2537-2543. doi: 10.1007/s00705-019-04330-w. Epub 2019 Jul 15.

Abstract

In May 2017, many free-ranging dorcas gazelles (Gazella dorcas) with suspected signs of peste des petits ruminants (PPR) were reported in Dinder National Park, South-Eastern Sudan. Peste des petits ruminants virus (PPRV) antigen and nucleic acid were detected in specimens from these gazelles using an immunocapture ELISA and a reverse transcription polymerase chain reaction (RT-PCR) assays. PPRV was also detected in four healthy semi-captive dorcas gazelles from two areas of Khartoum State. Phylogenetic analysis showed that these PPRV strains belonged to the lineage IV genotype. The present study demonstrates that gazelles are a potential wild small ruminant host for PPRV and may influence the epidemiology of PPR in the Sudan.

MeSH terms

  • Animals
  • Antelopes / virology*
  • Antigens, Viral / isolation & purification
  • Disease Reservoirs*
  • Enzyme-Linked Immunosorbent Assay
  • Genotype
  • Peste-des-Petits-Ruminants / virology*
  • Peste-des-petits-ruminants virus / classification
  • Peste-des-petits-ruminants virus / genetics
  • Peste-des-petits-ruminants virus / isolation & purification*
  • Phylogeny
  • RNA, Viral / isolation & purification
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Stomach Diseases
  • Sudan

Substances

  • Antigens, Viral
  • RNA, Viral