Antihyperglycemic therapy during colonoscopy preparation: A review and suggestions for practical recommendations

United European Gastroenterol J. 2019 Jul;7(6):735-740. doi: 10.1177/2050640619846365. Epub 2019 Apr 20.

Abstract

Patients with diabetes have distinct risks during precolonoscopy bowel preparation, caused by change of diet, change of antihyperglycemic medication regimens and diabetes-related complications and comorbidities. These risks include hypoglycemia, water and electrolyte imbalance, acute renal failure, lactic acidosis, ketoacidosis and low quality of bowel preparation. Here we review the existing literature and present recommendations from a subcommittee of the Israeli National Diabetes Council for primary care physicians and gastroenterologists. The instructions include general suggestions on diet and glucose monitoring and specific recommendations on timing of modification or cessation of each of the antihyperglycemic medication types to ensure patient safety during bowel preparation.

Keywords: Colonoscopy; epidemiology; nutrition; pancreas; screening.

Publication types

  • Review

MeSH terms

  • Blood Glucose
  • Colonoscopy* / adverse effects
  • Colonoscopy* / methods
  • Diabetes Mellitus / blood
  • Disease Management
  • Humans
  • Hypoglycemic Agents / administration & dosage*
  • Hypoglycemic Agents / adverse effects
  • Practice Guidelines as Topic
  • Preoperative Care*
  • Preoperative Period

Substances

  • Blood Glucose
  • Hypoglycemic Agents