Abstract
A histologic, histoimmunological, and ultrastructural study of a primary angiosarcoma of the thyroid gland is reported. The occurrence of neoplastic cells positive for Factor VIII-related antigen and Ulex Europaeus Agglutinin-I and the presence in their cytoplasms of Weibel-Palade bodies are consistent with this diagnosis. These findings further support the view that primary angiosarcoma of the thyroid is a distinct pathological entity and should no longer be interpreted as a variant of a poorly differentiated carcinoma.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Antigens / analysis
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Factor VIII / analysis
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Factor VIII / immunology
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Hemangiosarcoma / analysis
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Hemangiosarcoma / pathology*
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Hemangiosarcoma / ultrastructure
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Humans
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Immunohistochemistry
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Lectins / analysis
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Male
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Plant Lectins*
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Thyroid Neoplasms / analysis
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Thyroid Neoplasms / pathology*
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Thyroid Neoplasms / ultrastructure
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von Willebrand Factor
Substances
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Antigens
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Lectins
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Plant Lectins
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Ulex europaeus lectins
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von Willebrand Factor
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Factor VIII