Biochemical identification and characterization of the G antigen in the human blood group Rh

J Lirochon; C Doinel; P Rouger; D Goossens; C Salmon

Biochemical identification and characterization of the G antigen in the human blood group Rh

Immunology. 1988 Jun;64(2):337-40.

Authors

J Lirochon¹, C Doinel, P Rouger, D Goossens, C Salmon

Affiliation

¹ Fondation Nationale de Transfusion, Sanguine, Paris, France.

PMID: 3134298
PMCID: PMC1384965

Abstract

The human blood group Rh comprises erythrocyte membrane antigens which include the G antigen. In order to carry out this study, the G antigen was specifically immunofixed with a human monoclonal anti-Rh(G) antibody. After extraction and purification of the antigenic complex, a migration in SDS-PAGE showed the G antigen to be associated with a polypeptide of 28,000 MW.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal / immunology
Chromatography, Affinity
Electrophoresis, Polyacrylamide Gel
Erythrocytes / immunology
Humans
Molecular Weight
Rh-Hr Blood-Group System / immunology*

Substances

Antibodies, Monoclonal
Rh-Hr Blood-Group System