Ectopic ACTH Syndrome in a Child With Abdominal Ewing Sarcoma: A Rare Paraneoplastic Phenomenon

Abhinav K Tiwary; Barbara Greco; Matthew W Richardson

doi:10.1097/MPH.0000000000001569

Ectopic ACTH Syndrome in a Child With Abdominal Ewing Sarcoma: A Rare Paraneoplastic Phenomenon

J Pediatr Hematol Oncol. 2020 Oct;42(7):e668-e669. doi: 10.1097/MPH.0000000000001569.

Authors

Abhinav K Tiwary¹, Barbara Greco¹, Matthew W Richardson^{2

3}

Affiliations

¹ Baystate Medical Center.
² University of Massachusetts Medical School-Baystate.
³ Baystate Children's Hospital, Springfield, MA.

PMID: 31343485
DOI: 10.1097/MPH.0000000000001569

Abstract

Ectopic adrenocorticotropic hormone syndrome is a paraneoplastic phenomenon rarely seen in pediatrics and rarely described in Ewing sarcoma. We report a 15-year-old boy with abdominal Ewing sarcoma and clinical and laboratory findings of ectopic adrenocorticotropic hormone syndrome that promptly resolved with treatment of the tumor.

Publication types

Case Reports

MeSH terms

ACTH Syndrome, Ectopic / etiology
ACTH Syndrome, Ectopic / pathology*
ACTH Syndrome, Ectopic / therapy
Abdominal Neoplasms / complications*
Abdominal Neoplasms / pathology
Adolescent
Adrenocorticotropic Hormone / metabolism
Bone Neoplasms / complications*
Bone Neoplasms / pathology
Humans
Male
Prognosis
Sarcoma, Ewing / complications*
Sarcoma, Ewing / pathology

Substances

Adrenocorticotropic Hormone