Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

Michael Chavez; Lei S Qi

doi:10.1016/j.molcel.2019.07.004

Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

Mol Cell. 2019 Jul 25;75(2):206-208. doi: 10.1016/j.molcel.2019.07.004.

Authors

Michael Chavez¹, Lei S Qi²

Affiliations

¹ Department of Bioengineering, Stanford University, Stanford, CA, USA.
² Department of Bioengineering, Stanford University, Stanford, CA, USA; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA; ChEM-H, Stanford University, Stanford, CA, USA. Electronic address: [email protected].

PMID: 31348878
DOI: 10.1016/j.molcel.2019.07.004

Abstract

Discoveries by Klompe et al. (2019) and Strecker et al. (2019) elucidate distinct CRISPR-Cas mechanisms for site-specific programmable transposition in prokaryotic organisms.

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MeSH terms

CRISPR-Cas Systems*
Clustered Regularly Interspaced Short Palindromic Repeats*
DNA
RNA
Transposases

Substances

RNA
DNA
Transposases