An irregular, extremely broad QRS complex rhythm

Am J Emerg Med. 2019 Oct;37(10):1989.e1-1989.e3. doi: 10.1016/j.ajem.2019.158356. Epub 2019 Jul 21.

Abstract

We report a case of a 74-year-old lady admitted to the emergency department with a very broad QRS complex caused by flecainide intoxication due to acute renal failure. Appropriate recognition of the ECG changes and symptoms provoked by flecainide intoxication permitted quick directed treatment with intravenous administration of high dose sodium bicarbonate, which resolved the QRS elongation.

Keywords: Acute renal failure; Broad QRS complex; Drug toxicity; Flecainide.

Publication types

  • Case Reports

MeSH terms

  • Accidental Falls
  • Aged
  • Anti-Arrhythmia Agents / adverse effects*
  • Anti-Arrhythmia Agents / therapeutic use
  • Drug Overdose
  • Electrocardiography
  • Fatigue / chemically induced
  • Female
  • Flecainide / adverse effects*
  • Flecainide / therapeutic use
  • Humans
  • Sodium Bicarbonate / therapeutic use*
  • Tachycardia, Ventricular / chemically induced*
  • Tachycardia, Ventricular / drug therapy
  • Tachycardia, Ventricular / physiopathology
  • Treatment Outcome

Substances

  • Anti-Arrhythmia Agents
  • Sodium Bicarbonate
  • Flecainide