Y-graft modification to the Fontan procedure: Increasingly balanced flow over time

J Thorac Cardiovasc Surg. 2020 Feb;159(2):652-661. doi: 10.1016/j.jtcvs.2019.06.063. Epub 2019 Jul 10.

Abstract

Objective: The use of Y-grafts for Fontan completion is hypothesized to offer more balanced hepatic flow distribution (HFD) and decreased energy losses. The purpose of this study was to evaluate the hemodynamic performance of Y-grafts over time using serial cardiac magnetic resonance data and to compare their performance with extracardiac Fontan connections.

Methods: Ten Fontan patients with commercially available Y-graft connections and serial postoperative cardiac magnetic resonance data were included in this study. Patient-specific computational fluid dynamics simulations were used to estimate HFD and energy losses. Y-graft performance was compared with 3 extracardiac conduit Fontan groups (n = 10 for each) whose follow-up times straddle the Y-graft time points.

Results: Y-graft HFD became significantly more balanced over time (deviation from 50% decreased from 18% ± 14% to 8% ± 8%; P = .015). Total cavopulmonary connection resistance did not significantly change. Y-grafts at 3-year follow-up showed more balanced HFD than the extracardiac conduit groups at both the earlier and later follow-up times. Total cavopulmonary connection resistance was not significantly different between any Y-graft or extracardiac conduit group.

Conclusions: Y-grafts showed significantly more balanced HFD over a 3-year follow-up without an increase in total cavopulmonary connection resistance, and therefore may be a valuable option for Fontan completion. Additional follow-up data at longer follow-up times are still needed to thoroughly characterize the potential advantages of Y-graft use.

Keywords: Fontan; Y-graft; congenital heart disease; pulmonary arteriovenous malformations; single ventricle.

MeSH terms

  • Adolescent
  • Adult
  • Blood Vessel Prosthesis*
  • Child
  • Child, Preschool
  • Female
  • Fontan Procedure* / adverse effects
  • Fontan Procedure* / instrumentation
  • Fontan Procedure* / methods
  • Fontan Procedure* / statistics & numerical data
  • Heart Defects, Congenital / physiopathology
  • Heart Defects, Congenital / surgery
  • Hemodynamics / physiology*
  • Humans
  • Male
  • Prosthesis Design
  • Pulmonary Artery / physiology
  • Pulmonary Artery / surgery
  • Young Adult