[Individualization of dose and fractionation of radiotherapy for head and neck cancers]

Cancer Radiother. 2019 Oct;23(6-7):784-788. doi: 10.1016/j.canrad.2019.07.131. Epub 2019 Aug 13.
[Article in French]

Abstract

Head and neck cancers comprise a variety of tumours depending on the sub-site, for which target volumes and the prescribed doses need to be individualized according to each patient's history and presentation. This article aims at describing the main factors involved in decision-making regarding dose and volume, as well as ongoing research. Contouring and treatment guidelines, use of altered fractionation, major prognostic factors, the role of Human papillomavirus and of functional imaging will be presented and discussed.

Keywords: Cancer des voies aérodigestives supérieures; Cancer du nasopharynx; Chemotherapy; Epstein–Barr virus; Fractionation; Fractionnement; Head and neck cancer; Meta-analysis; Méta-analyse; Nasopharyngeal cancer; Radiotherapy; Radiothérapie; Virus d’Epstein-Barr; chimiothérapie.

Publication types

  • Review

MeSH terms

  • Dose Fractionation, Radiation
  • Head and Neck Neoplasms / diagnostic imaging
  • Head and Neck Neoplasms / radiotherapy*
  • Head and Neck Neoplasms / virology
  • Humans
  • Oropharyngeal Neoplasms / diagnostic imaging
  • Oropharyngeal Neoplasms / radiotherapy
  • Oropharyngeal Neoplasms / virology
  • Papillomaviridae
  • Positron-Emission Tomography
  • Practice Guidelines as Topic
  • Precision Medicine*
  • Prognosis
  • Radiotherapy Dosage*