Impact of an Antibiotic Stewardship Program on Antibiotic Prescription for Acute Respiratory Tract Infections in Children: A Prospective Before-After Study

Clin Pediatr (Phila). 2019 Oct;58(11-12):1166-1174. doi: 10.1177/0009922819870248. Epub 2019 Aug 20.

Abstract

We assessed the effectiveness of an antibiotic stewardship program (ASP) on antibiotic prescriptions for acute respiratory tract infection (ARTI) in a medical school. Our ASP included delivering an antibiotic use guideline via e-mail and LINE (an instant messaging app) to faculty staff, fellows, and residents, and posting of the guideline in examination rooms. Medical records of pediatric patients diagnosed with ARTI were reviewed to assess the appropriateness of antibiotic prescription. ASP could increase the rate of appropriateness from 78% (1979 out of 2553 visits) to 83.4% (2449 out of 2935 visits; P < .001). The baseline of appropriateness was higher in residents (95%) compared with fellows (82%) and faculty staff (75%). The ASP significantly increased the appropriateness only in faculty staff, especially in semiprivate clinics (75% to 83%, P < .001). In conclusion, our ASP increased appropriateness of antibiotic prescriptions for ARTI, with the greatest impact among faculty staff in semiprivate clinics.

Keywords: acute respiratory tract infection; antibiotic stewardship; medical school; pediatric; physician education.

MeSH terms

  • Acute Disease
  • Anti-Bacterial Agents / therapeutic use*
  • Antimicrobial Stewardship / statistics & numerical data*
  • Child
  • Child, Preschool
  • Controlled Before-After Studies
  • Drug Prescriptions / statistics & numerical data*
  • Faculty, Medical
  • Female
  • Humans
  • Inappropriate Prescribing / statistics & numerical data
  • Infant
  • Internship and Residency
  • Male
  • Pediatrics / statistics & numerical data
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Prospective Studies
  • Respiratory Tract Infections / drug therapy*
  • Thailand

Substances

  • Anti-Bacterial Agents