Childhood ocular mucous membrane pemphigoid successfully treated with rituximab

Pediatr Dermatol. 2019 Nov;36(6):984-985. doi: 10.1111/pde.13971. Epub 2019 Aug 25.

Abstract

Ocular mucous membrane pemphigoid (MMP) is a chronic autoimmune blistering disease that usually affects elderly patients being extremely rare in pediatric population. Despite aggressive immunosuppressive therapy, ocular MMP may progress causing significant morbidity. Herein, we describe a toddler with ocular MMP successfully treated with rituximab.

Keywords: immunobullous disease; mucous membrane disorders; systematic therapy; vesiculobullous disorders.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Humans
  • Immunologic Factors / therapeutic use*
  • Male
  • Pemphigoid, Benign Mucous Membrane / drug therapy*
  • Rituximab / therapeutic use*

Substances

  • Immunologic Factors
  • Rituximab