Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R

N Engl J Med. 2019 Aug 29;381(9):887-889. doi: 10.1056/NEJMc1806554.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy
  • Adult
  • Antitubercular Agents / therapeutic use
  • CD4 Lymphocyte Count
  • Drug Resistance, Viral / genetics*
  • Drug Therapy, Combination
  • HIV Infections / drug therapy*
  • HIV Infections / virology
  • HIV Integrase Inhibitors / therapeutic use*
  • HIV-1 / genetics*
  • Heterocyclic Compounds, 3-Ring / therapeutic use*
  • Humans
  • Male
  • Mutation*
  • Oxazines
  • Piperazines
  • Pyridones
  • Treatment Failure
  • Tuberculosis / complications
  • Tuberculosis / drug therapy
  • Viral Load / drug effects

Substances

  • Antitubercular Agents
  • HIV Integrase Inhibitors
  • Heterocyclic Compounds, 3-Ring
  • Oxazines
  • Piperazines
  • Pyridones
  • dolutegravir