Review and Update on Evidence-Based Surgical Treatment Recommendations for Nonmelanoma Skin Cancer

Dermatol Clin. 2019 Oct;37(4):425-433. doi: 10.1016/j.det.2019.05.002. Epub 2019 Jul 10.

Abstract

Nonmelanoma skin cancer (NMSC) is the most commonly diagnosed malignancy in the United States. Surgery is considered the gold standard treatment. Techniques include curettage and electrodesiccation, surgical excision, and Mohs micrographic surgery. While each is effective, there are relative advantages and disadvantages with respect to cost, time, quality of life, and role in patients with limited life expectancy. Preventing local tumor recurrence is the primary objective; however, recurrence rates are based on retrospective data, and high-quality comparator studies assessing effectiveness are scarce. Prospective and randomized controlled trials are imperative to create comprehensive, evidence-based recommendations for the surgical management of NMSC.

Keywords: Basal cell carcinoma; Curettage and electrodessication; Destruction; Excision; Mohs micrographic surgery; Nonmelanoma skin cancer; Squamous cell carcinoma; Surgical treatment.

Publication types

  • Review

MeSH terms

  • Carcinoma, Basal Cell / surgery*
  • Carcinoma, Squamous Cell / surgery*
  • Cost-Benefit Analysis
  • Curettage / methods
  • Decision Making, Shared
  • Dermatologic Surgical Procedures / methods
  • Desiccation / methods
  • Evidence-Based Medicine
  • Humans
  • Life Expectancy
  • Margins of Excision
  • Mohs Surgery / methods*
  • Patient Participation
  • Patient Preference
  • Patient Selection
  • Practice Guidelines as Topic
  • Skin Neoplasms / surgery*