New Insights and Treatments in Atopic Dermatitis

Pediatr Clin North Am. 2019 Oct;66(5):1021-1033. doi: 10.1016/j.pcl.2019.06.008.

Abstract

Atopic dermatitis is a complex, chronic inflammatory skin disorder with significant morbidity. It is often a frustrating condition for both children and parents due to chronic and relapsing course. There is now an increasing understanding of the disease pathogenesis resulting in discovery of much wanted newer therapeutics and targeted therapies after a long time. Whether these interventions will result in sustained benefits or long term cure remains to be seen.

Keywords: Atopic dermatitis; Atopic dermatitis phenotypes; Biologics; Small molecule inhibitors; Topical and systemic treatments.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use
  • Baths
  • Biological Products / therapeutic use
  • Child
  • Dermatitis, Atopic / immunology
  • Dermatitis, Atopic / physiopathology
  • Dermatitis, Atopic / therapy*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Immunotherapy
  • Phenotype
  • Phototherapy

Substances

  • Antibodies, Monoclonal
  • Biological Products
  • Immunosuppressive Agents