Atypical diagnosis for typical lung carcinoid

BMC Pulm Med. 2019 Sep 2;19(1):168. doi: 10.1186/s12890-019-0929-0.

Abstract

Background: The diagnosis of lung typical carcinoid tumors results challenging when limited size and unfavorable sampling location is associated. It has been reported that bronchoscopy with endobronchial ultrasound (EBUS) significantly increases the diagnostic yield of peripheral nodules smaller than 2 cm.

Case presentation: A 70-year-old Caucasian male complained of persistent fever and cough despite several antibiotic courses and steroid treatment. Chest radiology revealed the presence of a small single nodular opacity in the left upper lobe, whose standardized maximum uptake value (SUV) at fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) was significantly high (4.5). The patient underwent bronchial endoscopy but any appreciable sign of endobronchial or intramural involvement was detected. Only radial ultrasound-guided bronchoscopy (R-EBUS) allowed transbronchial sampling whose pathological analysis revealed a typical carcinoid tumor. The patients underwent surgical lobectomy and clinic-radiological follow was started.

Conclusions: With this case we aim at stressing the importance of ultrasound in the diagnostic process of lung small peripheral carcinoid, especially if they present without mucosal or sub mucosal involvement.

Keywords: Pulmonary carcinoid tumor; Solitary pulmonary nodule; Trans-bronchial biopsy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bronchoscopy
  • Carcinoid Tumor / diagnostic imaging*
  • Carcinoid Tumor / pathology
  • Carcinoid Tumor / surgery
  • Endosonography
  • Fluorodeoxyglucose F18
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / surgery
  • Male
  • Positron Emission Tomography Computed Tomography
  • Solitary Pulmonary Nodule / diagnostic imaging

Substances

  • Fluorodeoxyglucose F18