A(H9N2) influenza viruses associated with chicken mortality in outbreaks in Algeria 2017

Influenza Other Respir Viruses. 2019 Nov;13(6):622-626. doi: 10.1111/irv.12675. Epub 2019 Sep 3.

Abstract

In late 2017, increased mortality was detected in chicken farms in Algeria undergoing A(H9N2) influenza outbreaks. Analysis of viruses isolated from affected farms showed that they were monophyletic, were of the G1 hemagglutinin (HA) lineage, and were antigenically and genetically similar to viruses detected contemporaneously in other countries in Northern Africa and the Middle East. The virus was able to spread via contact transmission between ferrets but did not cause disease in intravenously inoculated chickens.

Keywords: Algeria; H9N2; influenza.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algeria / epidemiology
  • Animals
  • Chickens
  • Disease Outbreaks / veterinary*
  • Farms
  • Ferrets
  • Hemagglutination Inhibition Tests / veterinary
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics
  • Hemagglutinin Glycoproteins, Influenza Virus / immunology
  • Influenza A Virus, H9N2 Subtype / classification
  • Influenza A Virus, H9N2 Subtype / genetics
  • Influenza A Virus, H9N2 Subtype / immunology
  • Influenza A Virus, H9N2 Subtype / physiology*
  • Influenza in Birds / diagnosis
  • Influenza in Birds / epidemiology*
  • Influenza in Birds / transmission
  • Influenza in Birds / virology*
  • Neuraminidase / genetics
  • Phylogeny
  • Viral Load / veterinary
  • Viral Proteins / genetics

Substances

  • Hemagglutinin Glycoproteins, Influenza Virus
  • Viral Proteins
  • Neuraminidase

Associated data

  • GENBANK/MK240222
  • GENBANK/MK240305