Optic neuritis following anti-rabies vaccine

Ayush Agarwal; Divyani Garg; Vinay Goyal; Awadh K Pandit; Achal K Srivastava; Mv Padma Srivastava

doi:10.1177/0049475519872370

Optic neuritis following anti-rabies vaccine

Trop Doct. 2020 Jan;50(1):85-86. doi: 10.1177/0049475519872370. Epub 2019 Sep 7.

Authors

Ayush Agarwal¹, Divyani Garg², Vinay Goyal³, Awadh K Pandit⁴, Achal K Srivastava³, Mv Padma Srivastava⁵

Affiliations

¹ Senior Resident, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
² Assistant Professor, Department of Neurology, Lady Hardinge Medical College, New Delhi, India.
³ Professor, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
⁴ Assistant Professor, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
⁵ Professor and Head of Department, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

PMID: 31495273
DOI: 10.1177/0049475519872370

Abstract

Neurological complications related to anti-rabies vaccine are uncommon. The involvement of the optic nerve is extremely rare. It has been occasionally reported after Semple's vaccine administration due to the presence of highly antigenic sheep brain tissue in the vaccine. To our knowledge, this is the first case report of optic neuritis after chick embryo-derived anti-rabies vaccine.

Keywords: Optic neuritis; rabies; vaccine.

Publication types

Case Reports

MeSH terms

Adolescent
Animals
Chick Embryo
Humans
Male
Methylprednisolone / administration & dosage
Optic Neuritis / chemically induced*
Optic Neuritis / drug therapy
Optic Neuritis / pathology
Optic Neuritis / physiopathology
Rabies / prevention & control
Rabies Vaccines / administration & dosage
Rabies Vaccines / adverse effects*
Treatment Outcome

Substances

Rabies Vaccines
Methylprednisolone