Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux

Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3389-3404. doi: 10.1007/s00405-019-05631-1. Epub 2019 Sep 12.

Abstract

Objective: To develop clinical tools assessing the refluxogenic potential of foods and beverages (F&B) consumed by patients with laryngopharyngeal reflux (LPR).

Methods: European experts of the LPR Study group of the Young-Otolaryngologists of the International Federation of Oto-rhino-laryngological societies were invited to identify the components of Western European F&B that would be associated with the development of LPR. Based on the list generated by experts, four authors conducted a systematic review to identify the F&B involved in the development of esophageal sphincter and motility dysfunctions, both mechanisms involved in the development of gastroesophageal reflux disease and LPR. Regarding the F&B components and the characteristics identified as important in the development of reflux, experts developed three rational scores for the assessment of the refluxogenic potential of F&B, a dish, or the overall diet of the patient.

Results: Twenty-six European experts participated to the study and identified the following components of F&B as important in the development of LPR: pH; lipid, carbohydrate, protein composition; fiber composition of vegetables; alcohol degree; caffeine/theine composition; and high osmolality of beverage. A total of 72 relevant studies have contributed to identifying the Western European F&B that are highly susceptible to be involved in the development of reflux. The F&B characteristics were considered for developing a Refluxogenic Diet Score (REDS), allowing a categorization of F&B into five categories ranging from 1 (low refluxogenic F&B) to 5 (high refluxogenic F&B). From REDS, experts developed the Refluxogenic Score of a Dish (RESDI) and the Global Refluxogenic Diet Score (GRES), which allow the assessment of the refluxogenic potential of dish and the overall diet of the LPR patient, respectively.

Conclusion: REDS, RESDI and GRES are proposed as objective scores for assessing the refluxogenic potential of F&B composing a dish or the overall diet of LPR patients. Future studies are needed to study the correlation between these scores and the development of LPR according to impedance-pH study.

Keywords: Beverage; Diet; Food; Laryngitis; Laryngopharyngeal; Reflux; Score; Symptoms.

Publication types

  • Systematic Review

MeSH terms

  • Adult
  • Beverages*
  • Diet*
  • Electric Impedance
  • Esophagitis, Peptic
  • Female
  • Food*
  • Humans
  • Hydrogen-Ion Concentration
  • Laryngopharyngeal Reflux / diagnosis
  • Laryngopharyngeal Reflux / diet therapy*
  • Laryngopharyngeal Reflux / metabolism
  • Male
  • Middle Aged
  • Otolaryngologists*
  • Otolaryngology
  • Severity of Illness Index