The effects of high intensity-interval training on vaspin, adiponectin and leptin levels in women with polycystic ovary syndrome

Arch Physiol Biochem. 2022 Feb;128(1):37-42. doi: 10.1080/13813455.2019.1662450. Epub 2019 Sep 13.

Abstract

Aim: We aimed to investigate the metabolic effects of HIIT exercise on PCOS patients and how it affects adiponectin, vaspin and leptin.

Material and methods: Twenty women with PCOS were included in the study and were divided into two groups. HIIT program was applied for 10 PCOS and Medium Intensity Continuous Training (MICT) program was applied for other 10 PCOS. At the beginning and at the end of the study, total cholesterol, low-density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglyceride(TG), insulin, Adiponectin, Leptin, Vaspin levels of both PCOS groups were evaluated.

Results: When PCOS patients by performed HIIT exercise for 12 weeks, we found that the levels of leptin and vaspin did not change while adiponectin levels increased. Moreover serum levels of insulin, TG, total cholesterol, LDL-C decreased but levels of HDL-C increased.

Conclusion: HIIT increased in the adiponectin levels in women with PCOS and provided more weight loss.

Keywords: High intensity interval training; adiponectin; leptin; polycystic ovary syndrome; vaspin.

MeSH terms

  • Adiponectin / blood
  • Body Mass Index
  • Case-Control Studies
  • Female
  • High-Intensity Interval Training*
  • Humans
  • Insulin / blood
  • Insulin Resistance*
  • Leptin / blood
  • Polycystic Ovary Syndrome* / therapy
  • Serpins / blood

Substances

  • Adiponectin
  • Insulin
  • Leptin
  • SERPINA12 protein, human
  • Serpins