A practical thrice weekly ertapenem in hemodialysis patients

Yune-Fang Ueng; Hong-Jaan Wang; Shiao Chi Wu; Yee-Yung Ng

doi:10.1128/AAC.01427-19

A practical thrice weekly ertapenem in hemodialysis patients

Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01427-19. doi: 10.1128/AAC.01427-19. Epub 2019 Sep 16.

Authors

Yune-Fang Ueng^{1

2

3

4}, Hong-Jaan Wang⁵, Shiao Chi Wu⁶, Yee-Yung Ng^{7

8}

Affiliations

¹ Division of Basic Chinese Medicine, National Research Institute of Chinese Medicine, Taipei, Taiwan, Republic of China.
² Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan, Republic of China.
³ Institute of Biopharmaceutical Sciences, School of Pharmacy, National Yang-Ming University, Taipei, Taiwan, Republic of China.
⁴ Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
⁵ School of Pharmacy, National Defense Medical Center, Taipei, Taiwan, Republic of China.
⁶ Institute of Health and Welfare Policy, National Yang Ming University, Taipei, Taiwan, Republic of China.
⁷ Division of Nephrology, Taipei Veterans General Hospital, National Yang Ming University, Taiwan, Republic of China [email protected].
⁸ Department of Medicine, School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, Republic of China.

Abstract

Change of ertapenem dosage from 500 mg daily to thrice weekly after each hemodialysis session can maintain the plasma concentration above 2 mg/L, and be practical in hemodialysis patients.