CRISPR/Cas9-mediated gene deletion efficiently retards the progression of Philadelphia-positive acute lymphoblastic leukemia in a p210 BCR-ABL1^T315I mutation mouse model

Affiliations

• ¹ State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China [email protected] [email protected] [email protected] [email protected].
• ² Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
• ³ Present address: Eureka Therapeutics, Emeryville, CA, USA.
• ⁴ Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.
• ⁵ Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA, USA.
• ⁶ State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
• ⁷ Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.