This paper presents data on the distribution of IGHG1 phenotypes in three populations living in Italy (Albanians, Calabrians and Northern Italians). IGHG1 typing for the allotypes z, x, a, f has been performed by using standard antisera provided by the Central Laboratory of the Netherlands Red Cross Blood Transfusion Service (Amsterdam). The results are compared with those obtained for the same populations using alloantisera from polytransfused subjects and Behringwerke antisera. It is shown that the results obtained by using the different antisera are not in agreement. Moreover, standard antisera reveal that the IGHG1 za haplotype is more frequent in Albanians than in Northern Italians.