Common brain disorders are associated with heritable patterns of apparent aging of the brain

Affiliations

• ¹ NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. [email protected].
• ² NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
• ³ School of Mental Health and Neuroscience Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
• ⁴ Department of Psychiatry and Psychotherapy Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
• ⁵ Department of Psychiatry Diakonhjemmet Hospital, Oslo, Norway.
• ⁶ Centre for Psychiatry Research, Department of Clinical Neuroscience Karolinska Institutet & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
• ⁷ Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.
• ⁸ Department of Psychiatry Washington, University in St. Louis, St. Louis, USA.
• ⁹ Department of Radiology Washington, University in St. Louis, St. Louis, USA.
• ¹⁰ Department of Psychology I, University of Würzburg, Würzburg, Germany.
• ¹¹ Institute of Psychiatry Bari University Hospital, Bari, Italy.
• ¹² Department of Basic Medical Science, Neuroscience and Sense Organs University of Bari, Bari, Italy.
• ¹³ Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
• ¹⁴ Division of Radiology and Nuclear Medicine, Section of Neuroradiology Oslo University Hospital, Oslo, Norway.
• ¹⁵ Psychosomatic and CL Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
• ¹⁶ Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
• ¹⁷ Department of Psychiatry, Psychosomatics and Psychotherapy University of Lübeck, Lübeck, Germany.
• ¹⁸ Institute of Psychiatry King's College, London, UK.
• ¹⁹ Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center, Nijmegen, The Netherlands.
• ²⁰ Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.
• ²¹ Department of Neurology, Oslo University Hospital, Oslo, Norway.
• ²² Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University of Tübingen, Tübingen, Germany.
• ²³ Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA, USA.
• ²⁴ Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
• ²⁵ Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
• ²⁶ Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
• ²⁷ Division of Cognitive Neuroscience, University of Basel, Basel, Switzerland.
• ²⁸ Transfaculty Research Platform Molecular and Cognitive Neurosciences University of Basel, Basel, Switzerland.
• ²⁹ Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.
• ³⁰ NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
• ³¹ Department of Psychology, University of Oslo, Oslo, Norway.
• ³² Sunnaas Rehabilitation Hospital HT, Nesodden, Norway.
• ³³ Departments of Human Genetics and Psychiatry, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center, Nijmegen, The Netherlands.
• ³⁴ Department of Neuromedicine and Movement Science Norwegian, University of Science and Technology, Trondheim, Norway.
• ³⁵ Department of Radiology and Nuclear Medicine St. Olavs Hospital, Trondheim, Norway.
• ³⁶ Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
• ³⁷ Clinical Neuropsychology section Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
• ³⁸ Department of Cognitive Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
• ³⁹ Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
• ⁴⁰ Center for Human Development, University of California, San Diego, USA.
• ⁴¹ Department of Cognitive Science, University of California, San Diego, USA.
• ⁴² Departments of Psychiatry and Radiology, University of California, San Diego, USA.
• ⁴³ Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.
• ⁴⁴ Department of Clinical Psychology Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
• ⁴⁵ Bernstein Center for Computational Neuroscience Heidelberg/Mannheim, Mannheim, Germany.
• ⁴⁶ Department of Old Age Psychiatry and Psychotic Disorders Medical University of Lodz, Lodz, Poland.
• ⁴⁷ Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.
• ⁴⁸ Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine Sechenov First Moscow State Medical University, Moscow, Russia.
• ⁴⁹ Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS) Maastricht University, Maastricht, The Netherlands.
• ⁵⁰ Department of Psychiatry, Warneford Hospital University of Oxford, Oxford, UK.
• ⁵¹ Department of Biomedicine, University of Bergen, Bergen, Norway.
• ⁵² Mohn Medical Imaging and Visualization Centre, Department of Radiology, Haukeland University Hospital, Bergen, Norway.
• ⁵³ Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
• ⁵⁴ Department of Research and Education, Oslo University Hospital, Oslo, Norway.
• ⁵⁵ Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy.
• ⁵⁶ CatoSenteret Rehabilitation Center Son, Oslo, Norway.
• ⁵⁷ Departments of Radiation Sciences and Integrative Medical Biology, Umeå Center for Functional Brain Imaging Umeå University, Umeå, Sweden.
• ⁵⁸ Emma Children's Hospital, Amsterdam UMC University of Amsterdam and Vrije Universiteit Amsterdam, Emma Neuroscience Group, Department of Pediatrics, Amsterdam Reproduction & Development, Amsterdam, The Netherlands.
• ⁵⁹ Division of Molecular Neuroscience University of Basel, Basel, Switzerland.
• ⁶⁰ Life Sciences Training Facility, Department Biozentrum University of Basel, Basel, Switzerland.
• ⁶¹ Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.
• ⁶² Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway.
• ⁶³ Department of Neurology, Institute of Clinical Medicine University of Eastern Finland, Kuopio, Finland.
• ⁶⁴ Neurocenter, Neurology Kuopio University Hospital, Kuopio, Finland.
• ⁶⁵ Dr. E. Martens Research Group for Biological Psychiatry, Department of Medical Genetics Haukeland University Hospital, Bergen, Norway.
• ⁶⁶ 1st Department of Neurology Aristotle University of Thessaloniki, Thessaloniki, Greece.
• ⁶⁷ UMR Inserm 1027, CHU Toulouse, UPS, Toulouse, France.
• ⁶⁸ Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
• ⁶⁹ Department of Neurobiology Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
• ⁷⁰ District hospital Ansbach, Ansbach, Germany.
• ⁷¹ NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. [email protected].
• ⁷² Department of Psychology, University of Oslo, Oslo, Norway. [email protected].