2-Amino-3-cyano-4H-chromenes are structural core motifs that received increasing attention in the last years due to their interesting potential pharmacological properties. In this review, the synthetic methods for these compounds are classified based on the type of catalyst in the pertinent reactions. In addition, the wide range of pharmacological properties of these compounds is covered in a separate section.
Keywords: 2-Amino-4H-pyran-3-carbonitriles; Catalysts; Malononitrile; Pharmacological properties; Polysubstituted.