Functional assessment of glucocerebrosidase modulator efficacy in primary patient-derived macrophages is essential for drug development and patient stratification
1 Eisai-UCL Drug Discovery and Development Collaboration, UCL Queen Square Institute of Neurology, School of Life Sciences and Medicine, University College London, London.
2 Neurology Innovation Centre, Hatfield Research Laboratories, Eisai Ltd, Hatfield, Hertfordshire.
3 Lysosomal Storage Disorders Unit, Royal Free Hospital, London.
4 Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK [email protected].