The skull base is a part of the neuro-cranium formed by endochondral ossification. The embryological origin of the skull base is not perfectly known, but there seems to be an anterior region derived from the neural crest and a posterior part derived from the mesoderm. Further studies are needed to define reliable presumptive maps. The origin of the different components of the occipital bone is just as poorly known. Much fundamental work remains to be done to suggest any solution to these problems in humans.
Keywords: Cell interactions; Crête neurale; Interactions cellulaires; Mesoderm; Mésoderme; Neural crest; Somites.
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