Pyrrolidone-based polymers capable of reversible iodine capture for reuse in antibacterial applications

J Hazard Mater. 2020 Feb 15:384:121305. doi: 10.1016/j.jhazmat.2019.121305. Epub 2019 Sep 26.

Abstract

Numerous emerging and re-emerging advanced materials have been successful in capturing iodine pollutants that pose an unprecedented global challenge to public health. However, little attention has been paid to the reutilization of the captured iodine. Herein, we report on a pyrrolidone-based polymer capable of reversible iodine capture for reutilization in antibacterial applications. The pyrrolidone-based polymer poly(N-vinyl-2-pyrrolidone-co-vinyl acetate), denoted as P(VAc-NVP), was synthesized facilely via a one-step radical copolymerization strategy, and the synthesis was regulated by step-by-step optimization, specifically by tuning the feed ratio of NVP to VAc. The as-synthesized P(VAc-NVP) copolymer functioned as an adsorbent for iodine in various solutions, including water/ethanol, cyclohexane, and petroleum ether, in addition to having the special capability of releasing iodine in the presence of starch or bacteria. This opens up a new horizon for its functional practical use as a flexible adsorbent to capture iodine for safe disposal. Interestingly, the P(VAc-NVP) copolymer, after adsorbing iodine, showed antibacterial ability against pathogenic bacteria, including Staphylococcus aureus and Escherichia coli, when a series of simulated and practical antibacterial assays were conducted. It is believed that this proposed strategy based on the synergism of iodine capture and antibacterial use should have great potential for environmental remediation and public healthcare.

Keywords: Antibacterial use; Povidone-iodine; Pyrrolidone-based polymer; Reutilization; Reversible iodine capture.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology*
  • Escherichia coli / drug effects
  • Iodine / chemistry
  • Iodine / isolation & purification*
  • Iodine / pharmacology*
  • Microbial Sensitivity Tests
  • Polyvinyls / chemical synthesis
  • Polyvinyls / chemistry*
  • Pyrrolidinones / chemical synthesis
  • Pyrrolidinones / chemistry*
  • Staphylococcus aureus / drug effects
  • Water Pollutants, Chemical / chemistry
  • Water Pollutants, Chemical / isolation & purification
  • Water Pollutants, Chemical / pharmacology
  • Water Purification / methods

Substances

  • Anti-Bacterial Agents
  • Polyvinyls
  • Pyrrolidinones
  • Water Pollutants, Chemical
  • Iodine