Axons Gonna Ride 'til They Can't No More

Steven Boeynaems; Aaron D Gitler

doi:10.1016/j.neuron.2019.09.029

Axons Gonna Ride 'til They Can't No More

Neuron. 2019 Oct 23;104(2):179-181. doi: 10.1016/j.neuron.2019.09.029.

Authors

Steven Boeynaems¹, Aaron D Gitler²

Affiliations

¹ Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
² Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: [email protected].

PMID: 31647889
DOI: 10.1016/j.neuron.2019.09.029

Abstract

Prion-like domains have been implicated in protein phase separation and aggregation in cellular stress and neurodegeneration. In this issue of Neuron, Andrusiak et al. (2019) uncover a surprising role for a stress granule protein and phase separation in axon regeneration.

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MeSH terms

Axons*
Cytoplasmic Granules
Nerve Regeneration
Neurons
Prions*

Substances

Prions