Donor origin CAR19 T cell infusion for B-ALL relapsed after allogeneic hematopoietic stem cell transplantation

Xiaofei Yang; Haiping Dai; Liqing Kang; Changju Qu; Zheng Li; Jia Yin; Huiying Qiu; Chengcheng Fu; Yue Han; Zhengming Jin; Xiao Ma; Xiamin Zhu; Lei Yu; Depei Wu; Xiaowen Tang

doi:10.1002/hon.2682

Donor origin CAR19 T cell infusion for B-ALL relapsed after allogeneic hematopoietic stem cell transplantation

Hematol Oncol. 2019 Dec;37(5):655-658. doi: 10.1002/hon.2682. Epub 2019 Oct 27.

Authors

Xiaofei Yang^{1

2

3}, Haiping Dai^{1

2

3}, Liqing Kang^{4

5}, Changju Qu^{1

2

3}, Zheng Li^{1

2

3}, Jia Yin^{1

2

3}, Huiying Qiu^{1

2

3}, Chengcheng Fu^{1

2

3}, Yue Han^{1

2

3}, Zhengming Jin^{1

2

3}, Xiao Ma^{1

2

3}, Xiamin Zhu^{1

2

3}, Lei Yu^{4

5}, Depei Wu^{1

2

3}, Xiaowen Tang^{1

2

3}

Affiliations

¹ National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou, China.
² Institute of Blood and Marrow Transplantation, Suzhou, China.
³ Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
⁴ School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.
⁵ Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd, Shanghai, China.

PMID: 31656047
DOI: 10.1002/hon.2682

No abstract available

Publication types

Letter

MeSH terms

Antigens, CD19 / immunology*
Combined Modality Therapy
Hematopoietic Stem Cell Transplantation
Humans
Immunotherapy, Adoptive* / methods
Postoperative Care*
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / immunology*
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / mortality
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy*
Prognosis
Receptors, Antigen, T-Cell / genetics
Receptors, Antigen, T-Cell / metabolism*
Receptors, Chimeric Antigen / genetics
Receptors, Chimeric Antigen / metabolism*
Transplantation, Homologous
Treatment Outcome

Substances

Antigens, CD19
Receptors, Antigen, T-Cell
Receptors, Chimeric Antigen

Publication types

MeSH terms

Substances

Grants and funding