Successful intravenous thrombolysis for ischemic stroke as a complication of coronary intervention in patients with ticagrelor pretreatment

J Clin Neurosci. 2020 Jan:71:283-286. doi: 10.1016/j.jocn.2019.10.007. Epub 2019 Oct 26.

Abstract

Ticagrelor is an antiplatelet agent used for treatment of coronary artery disease via inhibition of the P2Y12 receptor. Based on limited literature the safety of intravenous thrombolysis for ischemic stroke in patients with ticagrelor pretreatment is unknown. We present two patients established on ticagrelor treated with intravenous thrombolysis for acute ischemic stroke complicating coronary intervention.

Keywords: Ischemic stroke; Thrombolysis; Ticagrelor.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiovascular Surgical Procedures / adverse effects*
  • Coronary Artery Disease / drug therapy*
  • Coronary Artery Disease / surgery*
  • Humans
  • Male
  • Middle Aged
  • Platelet Aggregation Inhibitors / therapeutic use
  • Stroke / drug therapy
  • Stroke / etiology*
  • Thrombolytic Therapy / methods
  • Ticagrelor / therapeutic use*
  • Treatment Outcome

Substances

  • Platelet Aggregation Inhibitors
  • Ticagrelor