Occupational Exposure to the Ugandan Research Strain (MR766) of Zika Virus

Paola N Lichtenberger; Michael J Ricciardi; Dalhila Solorzano; Patricia Raccamarich; Ana Leda; Mark Sharkey; David I Watkins; Hana El Sahly; Nadine Rouphael; Mark J Mulligan; Susanne Doblecki-Lewis; Mario Stevenson; Maria L Alcaide

doi:10.1093/ofid/ofz420

Occupational Exposure to the Ugandan Research Strain (MR766) of Zika Virus

Open Forum Infect Dis. 2019 Oct 25;6(10):ofz420. doi: 10.1093/ofid/ofz420. eCollection 2019 Oct.

Affiliations

¹ Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA.
² Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA.
³ Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida, USA.
⁴ Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
⁵ Department of Medicine, Emory University, Atlanta, Georgia, USA.
⁶ New York University Vaccine Center and Division of Infectious Diseases and Immunology, Department of Medicine, New York University School of Medicine, New York, New York, USA.

Abstract

A laboratory worker suffered an accidental needle-stick resulting in an exposure to the Ugandan strain (MR766) of Zika virus, which has rarely been studied in humans. We report the clinical presentation and outcomes, molecular and serological diagnostic results, and antibody response.

Keywords: ZIKV; antibody responses; occupational exposure; viral persistence.

Publication types

Case Reports

Grants and funding

U01 AI047996/AI/NIAID NIH HHS/United States